Bias

You see my worry with basic medical research? When experimental methods are limited to radioimmunoassay and western blotting and qualitative polymerase chain reaction, a medical scientist needs to have a thorough understanding of the field that he is working on and then formulate a research hypothesis. Then he conducts experiments to prove (or disprove) that hypothesis.

But, now, with genomics and transcriptomes and proteomics and all similarly complex methods, medical research leaps to a new era: Scientists don't need a hypothesis to start some work (and, for that reason, they may not quite understand the field that they are working on). Proponents of this approach claim that it is hypothesis-free and therefore bias-free.

Well, that may be true. Bias requires neuronal activity to develop. For sure we will not have bias if we don't use our brain.

Or, is it the real meaning of Great intelligence may appear as stupidity (大智若愚)?